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Phospho-MCL1-T163 Rabbit Polyclonal Antibody (CABP0943)

SKU:
CABP0943
Product Type:
Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Death
€419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Phospho-MCL1-T163 Rabbit Polyclonal Antibody
SKU:CABP0943
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse
Immunogen:A synthetic phosphorylated peptide around T163 of human MCL1 (NP_068779.1).
Sequence:PSTP P
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:2000
Synonyms:TM; EAT; MCL1L; MCL1S; Mcl-1; BCL2L3; MCL1-ES; bcl2-L-3; mcl1/EAT; Phospho-MCL1-T163
Positive Sample:NIH/3T3
Cellular Localization:Cytoplasm, Membrane, Mitochondrion, Nucleus, Single-pass membrane protein, nucleoplasm.
Calculated MW:37kDa
Observed MW:41kDa

This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing.

Purification Method:Affinity purification
Gene ID:4170
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from NIH/3T3 cells, using Phospho-MCL1-T163 Rabbit pAb (CABP0943) at 1:1000 dilution.NIH/3T3 cells were treated by PMA (80 nM) for overnight.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% BSA.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.

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