Based on the information provided in the URL, the Phospho-MAP3K9/MAP3K10 (T312/266) Antibody (PAC004335) is a valuable tool for researchers studying the MAP3K9 and MAP3K10 proteins, which are involved in various signaling pathways within the cell. This antibody is specific for the phosphorylated form of MAP3K9 and MAP3K10 at threonine 312 and serine 266, respectively.The antibody is produced using high-quality materials and has been validated for use in applications such as Western blotting, immunohistochemistry, and immunofluorescence. By targeting the phosphorylated forms of MAP3K9 and MAP3K10, researchers can better understand the activation and regulation of these proteins in cellular processes such as cell growth, differentiation, and apoptosis.
This antibody is particularly useful for studies in the fields of cell signaling, cancer biology, and drug development, where the MAP3K9 and MAP3K10 proteins are known to play important roles. By using this antibody, researchers can gain insights into the function and behavior of these proteins in both normal and diseased cells, leading to advancements in our understanding of cellular signaling pathways and potential therapeutic targets.
Antibody Name:
Phospho-MAP3K9/MAP3K10 (T312/266) Antibody
Antibody SKU:
PACO04335
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
IHC:1:100-1:300
Species Reactivity:
Human, Mouse
Immunogen:
synthesized peptide derived from human MLK1/2 around the phosphorylation site of T312/266.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
MAP3K9; MLK1; PRKE1; Mitogen-activated protein kinase kinase kinase 9; Mixed lineage kinase 1; MAP3K10; MLK2; MST; Mitogen-activated protein kinase kinase kinase 10; Mixed lineage kinase 2; Protein kinase MST
UniProt Protein Function:
MLK1: a TKL kinase of the MLK family. A dual leucine zipper kinase. Expressed in neuronal cells and may act between Rac1/Cdc42 and MKK4 and -7 in death signaling. Protein type: Kinase, protein; Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.25; Protein kinase, TKL; TKL group; MLK family; MLK subfamilyChromosomal Location of Human Ortholog: 14q24.2Molecular Function: JUN kinase kinase kinase activity; protein binding; protein homodimerization activity; protein serine/threonine kinase activityBiological Process: activation of JNK activity; protein amino acid autophosphorylation; protein amino acid phosphorylation
