The MEK7 Rabbit Monoclonal Antibody is a valuable tool for researchers studying the MEK7 protein, a key player in the MAPK signaling pathway that regulates cell growth, proliferation, and differentiation. This antibody is specifically designed for use in immunohistochemistry, western blotting, and flow cytometry, offering high sensitivity and specificity in detecting MEK7 expression in various cell types and tissues.MEK7, also known as MAP2K7, is a crucial component of the MAPK pathway that mediates cellular responses to extracellular signals, making it a promising target for studying diseases such as cancer, inflammatory disorders, and neurodegenerative diseases.
By using the MEK7 Rabbit Monoclonal Antibody, researchers can gain valuable insights into the role of MEK7 in these pathologies and potentially identify new therapeutic targets for intervention.Overall, the MEK7 Rabbit Monoclonal Antibody is a reliable tool for investigating the function of MEK7 in cellular signaling pathways and disease pathogenesis, making it an essential component of any research project focused on understanding MAPK signaling and its implications in human health and disease.
Product Name:
MEK7 Rabbit Monoclonal Antibody
SKU:
CAB12950
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 320-419 of human MEK7 (O14733).
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
5609
Clone Number:
ARC0712
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type(WT) and MEK7 knockout (KO) 293T(KO) cells, using [KO Validated] MEK7 Rabbit mAb (CAB12950) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
