MEK1/MEK2 Rabbit Polyclonal Antibody (CAB18117)
- SKU:
- CAB18117
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | MEK1/MEK2 Rabbit Polyclonal Antibody |
SKU: | CAB18117 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 200-300 of human MAP2K1 (NP_002746.1). |
Sequence: | SRGE IKLC DFGV SGQL IDSM ANSF VGTR SYMS PERL QGTH YSVQ SDIW SMGL SLVE MAVG RYPI PPPD AKEL ELMF GCQV EGDA AETP PRPR TPGR PLSS Y |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:100 - 1:500 |
Synonyms: | MEK1/MEK2 |
Positive Sample: | mouse brain,mouse spleen,PC-12 |
Conjugate: | Unconjugated |
Cellular Localization: | cytosol, early endosome, endoplasmic reticulum, focal adhesion, Golgi apparatus, late endosome, microtubule organizing center, mitochondrion, nucleus, plasma membrane |
Calculated MW: | 40kDa/43kDa/44kDa |
Observed MW: | 44kDa |
The protein MEK1 and MEK2 are two members of the dual specificity protein kinase family, which act as mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.
Purification Method: | Affinity purification |
Gene ID: | 5604/5605 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |