The LIPE Polyclonal Antibody (CAB15686) is a valuable tool for researchers studying LIPE, a key enzyme involved in lipid metabolism. This antibody, produced in rabbits, is highly specific to LIPE and validated for use in various applications, including Western blotting. By binding to the LIPE protein, this antibody allows for the detection and analysis of LIPE in different cell types, making it a versatile option for studies in metabolism, obesity, and related diseases.LIPE, also known as hormone-sensitive lipase, plays a crucial role in the breakdown of stored fats for energy production. Dysregulation of LIPE activity has been linked to metabolic disorders such as obesity, diabetes, and cardiovascular diseases.
Investigating the function of LIPE can provide valuable insights into the underlying mechanisms of these conditions and may lead to the development of novel therapeutic strategies targeting lipid metabolism.Overall, the LIPE Polyclonal Antibody is a reliable tool for researchers seeking to explore the role of LIPE in metabolic processes and associated diseases. Its specificity and sensitivity make it a valuable asset for advancing our understanding of lipid metabolism and its implications for human health.
Product Name:
HSL Rabbit Polyclonal Antibody
SKU:
CAB15686
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 900-1000 of human LIPE (NP_005348.2).
The protein encoded by this gene has a long and a short form, generated by use of alternative translational start codons. The long form is expressed in steroidogenic tissues such as testis, where it converts cholesteryl esters to free cholesterol for steroid hormone production. The short form is expressed in adipose tissue, among others, where it hydrolyzes stored triglycerides to free fatty acids.
Purification Method:
Affinity purification
Gene ID:
3991
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of Mouse adipose, using HSL Rabbit pAb (CAB15686) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
