The JUN Polyclonal Antibody (CAB0246) is a valuable tool for research involving the JUN protein, a transcription factor that plays a critical role in cell proliferation, differentiation, and apoptosis. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in various applications, including Western blot and immunohistochemistry. By binding specifically to the JUN protein, this antibody allows for the detection and analysis of JUN expression in a wide range of cell types.JUN is a key player in gene regulation, controlling the expression of genes involved in processes such as cell growth, survival, and response to stress.
Dysregulation of JUN expression has been implicated in various diseases, including cancer, inflammatory disorders, and neurodegenerative conditions. Studying the role of JUN in these diseases can provide valuable insights into disease mechanisms and potentially lead to the development of targeted therapies.Overall, the JUN Polyclonal Antibody (CAB0246) is a highly sensitive and specific tool for investigating the function of the JUN protein in a variety of research contexts. Its versatility and reliability make it a valuable asset for researchers in the fields of molecular biology, cell biology, and cancer research.
Product Name:
c-Jun Rabbit Polyclonal Antibody
SKU:
CAB0246
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 90-230 of c-Jun (NP_002219.1).
This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies.
Purification Method:
Affinity purification
Gene ID:
3725
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using c-Jun Rabbit pAb (CAB0246) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
