The Phospho-Jun (S73) Polyclonal Antibody (CABP0119) is a valuable tool for researchers studying the phosphorylation of the Jun protein at serine 73. This antibody, produced in rabbits, has high reactivity with human samples and has been validated for use in Western blotting applications.Phosphorylation at serine 73 plays a crucial role in the regulation of Jun, a transcription factor that is involved in various cellular processes such as cell proliferation, apoptosis, and differentiation. Understanding the phosphorylation of Jun at this specific site is important for unraveling its complex regulatory mechanisms and its impact on cell signaling pathways.
Researchers in the fields of cell biology, molecular biology, and cancer research can benefit from using this antibody to investigate the role of phosphorylated Jun in various cellular processes and pathological conditions. By enabling the detection and analysis of phosphorylated Jun at serine 73, this antibody contributes to advancing our understanding of the intricate molecular mechanisms governing cell behavior and disease development.
Product Name:
Phospho-c-Jun-S73 Rabbit Polyclonal Antibody
SKU:
CABP0119
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic phosphorylated peptide around S73 of human c-JUN (NP_002219.1).
Sequence:
LASP E
Tested Applications:
WBIHC-PELISA
Recommended Dilution:
WB,1:500 - 1:1000 IHC-P,1:50 - 1:200
Synonyms:
AP1; p39; AP-1; cJUN; c-Jun; Phospho-c-Jun-S73
Positive Sample:
PC-14
Conjugate:
Unconjugated
Cellular Localization:
Nucleus.
Calculated MW:
36kDa
Observed MW:
42kDa
This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies.
Purification Method:
Affinity purification
Gene ID:
3725
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from PC14 cells using Phospho-c-Jun-S73 Rabbit pAb (CABP0119).Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% BSA.
