Phospho-HSP27/HSPB1-S82 Rabbit Monoclonal Antibody (CABP1031)
- SKU:
- CABP1031
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | Phospho-HSP27/HSPB1-S82 Rabbit Monoclonal Antibody |
SKU: | CABP1031 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Rat |
Immunogen: | A synthetic phosphorylated peptide around S82 of human HSP27/HSPB1HSPB1 (P04792). |
Sequence: | QLSS G |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | CMT2F; HMN2B; HSP27; HSP28; Hsp25; SRP27; HS.76067; HEL-S-102; Phospho-HSP27/HSPB1-S82 |
Positive Sample: | HeLa treated by UV,PC-12 treated by CIP or UV |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus, Cytoskeleton, Spindle. |
Calculated MW: | 23kDa |
Observed MW: | 27kDa |
This gene encodes a member of the small heat shock protein (HSP20) family of proteins. In response to environmental stress, the encoded protein translocates from the cytoplasm to the nucleus and functions as a molecular chaperone that promotes the correct folding of other proteins. This protein plays an important role in the differentiation of a wide variety of cell types. Expression of this gene is correlated with poor clinical outcome in multiple human cancers, and the encoded protein may promote cancer cell proliferation and metastasis, while protecting cancer cells from apoptosis. Mutations in this gene have been identified in human patients with Charcot-Marie-Tooth disease and distal hereditary motor neuropathy.
Purification Method: | Affinity purification |
Gene ID: | 3315 |
Clone Number: | ARC1576 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |