The Phospho-HNF4A (S304) Polyclonal Antibody (CABP0362) offered by AssayGenie is a key tool for researchers studying the phosphorylation of the HNF4A protein. HNF4A is a nuclear receptor that plays a critical role in regulating gene expression, particularly in the liver and pancreas. The phosphorylation of HNF4A at serine 304 has been shown to impact its activity and function, making this antibody essential for understanding the regulatory mechanisms involving HNF4A.Raised in rabbits, this antibody is highly specific and reactive with human samples, making it a reliable tool for Western blot applications. By detecting and analyzing the phosphorylation status of HNF4A at serine 304, researchers can gain insights into how this modification influences the protein's function in various cellular processes.
This antibody is ideal for studies in molecular biology, cell signaling, and metabolic disorders where HNF4A is known to be involved.In summary, the Phospho-HNF4A (S304) Polyclonal Antibody from AssayGenie is a valuable resource for researchers investigating the role of HNF4A phosphorylation in gene regulation and disease pathways. Its high specificity and sensitivity make it a trusted tool for uncovering the complex regulatory networks involving HNF4A in different cellular contexts.
Product Name:
Phospho-HNF4A-S304 Rabbit Polyclonal Antibody
SKU:
CABP0362
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic phosphorylated peptide around S304 of human HNF4A (NP_849180.1).
The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms.
Purification Method:
Affinity purification
Gene ID:
3172
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from HeLa cells, using Phospho-HNF4A-S304 Rabbit pAb (CABP0362).Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% BSA.
