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Phospho-Histone H3 (T11) Antibody (PACO05460)

SKU:
PACO05460
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
IF
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€269
Frequently bought together:

Description

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Phospho-Histone H3 (T11) Antibody (PACO05460)

The Phospho-Histone H3 (T11) Polyclonal Antibody (PACO05460) is a valuable tool for researchers studying cell division and chromatin structure. This antibody is highly specific for phosphorylated Histone H3 at Threonine 11, a critical post-translational modification involved in regulating chromatin condensation and mitotic progression. Raised in rabbits, the PACO05460 antibody is validated for use in various applications, including Western blot and immunohistochemistry, with high reactivity towards human samples. By targeting this specific phosphorylation site on Histone H3, researchers can investigate the dynamics of chromatin remodeling during cell division and unravel the intricate regulatory mechanisms governing cell cycle progression.

Histone H3 phosphorylation at Threonine 11 has been implicated in mitotic spindle assembly, chromosome segregation, and DNA damage response, making it a key player in maintaining genomic stability and cell proliferation. By utilizing the PACO05460 antibody, researchers can dissect the role of this post-translational modification in various cellular processes, shedding light on its implications for cancer biology, developmental biology, and other fields of study.