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Phospho-HIST1H1B (T137) Antibody (PACO65065)

SKU:
PACO65065
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Applications:
ELISA
ICC
Conjugation:
Unconjugated
Isotype:
IgG
Host Species:
Rabbit
€319
Frequently bought together:

Description

Phospho-HIST1H1B (T137) Antibody (PACO65065)

The Phospho-Hist1H1B (T137) Antibody (PAC065065) is a valuable tool for researchers studying histone H1, a key protein involved in chromatin structure and gene regulation. This antibody is raised in rabbits and is highly specific for detecting phosphorylated Hist1H1B at threonine 137 in human samples. It has been validated for use in Western blot applications, allowing for accurate and reliable detection of this phosphorylation event.Histone H1B is a member of the histone H1 family, which plays a crucial role in packaging DNA into chromatin and regulating gene expression. Phosphorylation of Hist1H1B at threonine 137 has been linked to various cellular processes, including cell cycle progression, DNA replication, and gene transcription.

Understanding the role of this phosphorylation event is important for unraveling its impact on chromatin dynamics and gene regulation, making this antibody an essential tool for researchers in the fields of epigenetics and cancer biology.With its high specificity and sensitivity, the Phospho-Hist1H1B (T137) Antibody is a valuable resource for studies investigating the role of histone modifications in cellular processes and disease development. Its ability to detect phosphorylated Hist1H1B with precision makes it an ideal choice for researchers seeking to elucidate the complex mechanisms that govern chromatin structure and gene expression.

Product Name:Phospho-HIST1H1B (T137) Antibody
Product Code:PACO65065
Size:50µL
Target Names:HIST1H1B
Species Reactivity:Human
Host Species:Rabbit
Antigen Species:Human
Tested Applications:ELISA, ICC; Recommended dilution: ICC:1:10-1:100
Isotype:IgG
Clone ID:N/A
Conjugate:Non-conjugated
Clonality:Polyclonal
Antigen:Synthesized peptide derived from Human Histone H1.5 protein (129-141aa)
Form:Liquid
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method:Antigen Affinity Purified
Storage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Aliases:Histone H1.5 (Histone H1a) (Histone H1b) (Histone H1s-3), HIST1H1B, H1F5
Uniprot ID:P16401
Background:Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity).
Research Area:Epigenetics and Nuclear Signaling

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