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Phospho-HIST1H1B (S188) Antibody (PACO65064)

SKU:
PACO65064
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Applications:
ELISA
ICC
Conjugation:
Unconjugated
Isotype:
IgG
Host Species:
Rabbit
€319
Frequently bought together:

Description

Phospho-HIST1H1B (S188) Antibody (PACO65064)

The Phospho-Hist1H1B (S188) Antibody (PAC065064) is a valuable tool for researchers studying post-translational modifications of Hist1H1B, a histone protein involved in the regulation of gene expression and chromatin structure. This antibody, generated in rabbits, is highly specific for detecting phosphorylation of Hist1H1B at serine 188 in human samples. Validated for use in Western blot applications, it enables researchers to investigate the role of Hist1H1B phosphorylation in various cellular processes.Histone phosphorylation is a key mechanism for regulating gene expression and chromatin dynamics, contributing to diverse biological processes such as cell cycle progression, DNA repair, and apoptosis.

Phosphorylation of Hist1H1B at serine 188 has been implicated in specific signaling pathways and cellular responses, making this antibody a valuable tool for studying the molecular mechanisms underlying these processes.By targeting the phosphorylated form of Hist1H1B, researchers can gain insights into how this modification influences chromatin structure and gene expression, providing a deeper understanding of cellular function and potential therapeutic targets. The Phospho-Hist1H1B (S188) Antibody is ideal for investigations in epigenetics, cell signaling, and cancer research, offering new opportunities for uncovering the role of Hist1H1B phosphorylation in health and disease.

Product Name:Phospho-HIST1H1B (S188) Antibody
Product Code:PACO65064
Size:50µL
Target Names:HIST1H1B
Species Reactivity:Human
Host Species:Rabbit
Antigen Species:Human
Tested Applications:ELISA, ICC; Recommended dilution: ICC:1:10-1:100
Isotype:IgG
Clone ID:N/A
Conjugate:Non-conjugated
Clonality:Polyclonal
Antigen:Synthesized peptide derived from Human Histone H1.5 protein (184-196aa)
Form:Liquid
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method:Antigen Affinity Purified
Storage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Aliases:Histone H1.5 (Histone H1a) (Histone H1b) (Histone H1s-3), HIST1H1B, H1F5
Uniprot ID:P16401
Background:Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity).
Research Area:Epigenetics and Nuclear Signaling

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