Phospho-HIST1H1B (S172) Antibody (PACO65025)
- SKU:
- PACO65025
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Applications:
- ELISA
- ICC
- Conjugation:
- Unconjugated
- Isotype:
- IgG
- Host Species:
- Rabbit
Description
Phospho-HIST1H1B (S172) Antibody (PACO65025)
The Phospho-Hist1H1B (S172) Antibody (PAC065025) is a valuable tool for researchers studying phosphorylation events in the Histone H1 family of proteins. This antibody, raised in rabbits, specifically recognizes the phosphorylated form of Hist1H1B at serine 172, making it ideal for Western blot applications in human samples.Histone H1 proteins play a crucial role in chromatin structure and gene regulation, and phosphorylation of these proteins can impact gene expression and cellular processes. The Phospho-Hist1H1B (S172) Antibody allows for the detection and analysis of phosphorylated Hist1H1B in various cell types, providing insights into the regulatory mechanisms of histone phosphorylation in normal and disease states.
By understanding the phosphorylation events of Histone H1 proteins, researchers can further unravel the complexities of epigenetic regulation and its implications in various diseases, including cancer, developmental disorders, and neurodegenerative diseases. The use of the Phospho-Hist1H1B (S172) Antibody in research studies will contribute to advancements in the field of epigenetics and potentially lead to the development of targeted therapies.
Product Name: | Phospho-HIST1H1B (S172) Antibody |
Product Code: | PACO65025 |
Size: | 50µL |
Target Names: | HIST1H1B |
Species Reactivity: | Human |
Host Species: | Rabbit |
Antigen Species: | Human |
Tested Applications: | ELISA, ICC; Recommended dilution: ICC:1:10-1:100 |
Isotype: | IgG |
Clone ID: | N/A |
Conjugate: | Non-conjugated |
Clonality: | Polyclonal |
Antigen: | Synthesized peptide derived from Human Histone H1.5 protein (164-176aa) |
Form: | Liquid |
Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | Antigen Affinity Purified |
Storage: | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Aliases: | Histone H1.5 (Histone H1a) (Histone H1b) (Histone H1s-3), HIST1H1B, H1F5 |
Uniprot ID: | P16401 |
Background: | Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity). |
Research Area: | Epigenetics and Nuclear Signaling |