Phospho-HDAC7A (Ser155) In-Cell ELISA- High Sensitivity

Phospho-HDAC7A (Ser155) In-Cell ELISA

SKU:

CBCAB01700

Product Type:

ELISA Kit

ELISA Type:

Cell Based Phospho Specific

Research Area:

Epigenetics and Nuclear Signaling

Reactivity:

Human

Mouse

Rat

Detection Method:

Colorimetric

Description

Description

MSDS

Phospho-HDAC7A (Ser155) Cell-Based ELISA

Product Description:	The Phospho-HDAC7A (Ser155) Colorimetric Cell-Based ELISA Kit allows for qualitative detection of Phospho-HDAC7A(Ser155) in plated and fixed cells.
Target Synonyms:	HD7a; HDA7; HDAC7A; Histone deacetylase 7a
Detection Target:	Phospho-IRAK1(Thr209)
Reactivity:	H:S155, M:S178, R:S164
Pack Size:	2 x 96 assays
Detection Method:	Colorimetric 450 nm
Format:	Cell-Based ELISA/In-Cell ELISA
Storage and Stability Guarantee:	4 °C/6 Months
Sample Type:	Plated & fixed cells
Range:	5000 cells/well minimum
Time:	4.5 hours

Phospho-HDAC7A (Ser155) Cell-Based ELISA Protein Information

UniProt Protein Function:	Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer factors such as MEF2A, MEF2B and MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors. May be involved in Epstein-Barr virus (EBV) latency, possibly by repressing the viral BZLF1 gene. Positively regulates the transcriptional repressor activity of FOXP3 (PubMed:17360565).
NCBI Summary:	Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Code:	Q8WUI4
NCBI GenInfo Identifier:	30913097
NCBI Gene ID:	51564
NCBI Accession:	Q8WUI4.2
UniProt Secondary Accession:	Q8WUI4,Q6P1W9, Q6W9G7, Q7Z4K2, Q7Z5I1, Q96K01, Q9BR73 Q9H7L0, Q9NW41, B3KY08, B4DWI0, B4E0Q5,
UniProt Related Accession:	Q8WUI4
Molecular Weight:	66,187 Da
NCBI Full Name:	Histone deacetylase 7
NCBI Synonym Full Names:	histone deacetylase 7
NCBI Official Symbol:	HDAC7
NCBI Official Synonym Symbols:	HD7; HD7A; HDAC7A
NCBI Protein Information:	histone deacetylase 7
UniProt Protein Name:	Histone deacetylase 7
UniProt Synonym Protein Names:	Histone deacetylase 7A; HD7a
Protein Family:	Histone deacetylase
UniProt Gene Name:	HDAC7
UniProt Entry Name:	HDAC7_HUMAN

Phospho-HDAC7A (Ser155)In-Cell ELISA

The Phospho-HDAC7 (Ser155) In-Cell ELISA Kit is a valuable tool for the accurate detection and quantification of phosphorylated HDAC7 (Ser155) levels in cellular samples. This kit offers high sensitivity and specificity, ensuring precise and reliable results for researchers studying the role of HDAC7 phosphorylation in various cellular processes.HDAC7 is a key regulator of gene expression and plays a critical role in various cellular functions, including cell growth, differentiation, and apoptosis. Phosphorylation of HDAC7 at Ser155 has been shown to impact its activity and subcellular localization, making it a crucial modification for understanding HDAC7-mediated signaling pathways.

With the Phospho-HDAC7 (Ser155) In-Cell ELISA Kit, researchers can accurately measure the levels of phosphorylated HDAC7 in cell lysates, providing valuable insights into the regulation of HDAC7 activity and its potential implications in disease states. This kit is suitable for a wide range of research applications, making it a valuable tool for studying the complex role of HDAC7 in cellular physiology and pathology.

Antibodies

Anti-HDAC7 Antibody (CAB13008)

Anti-HDAC7 Antibody (CAB16532)

Anti-HDAC7 Antibody (CAB2970)

Anti-HDAC7 Antibody (CAB7285)

HDAC7A Antibody (PACO00910)