The Phospho-HDAC4 (S632) Polyclonal Antibody (CABP0359) is a valuable tool for researchers studying the regulation of HDAC4 through phosphorylation. This antibody, produced in rabbits, is highly specific for detecting phosphorylated HDAC4 at serine 632 in human samples, and has been validated for use in Western blot applications.HDAC4 is a key player in epigenetic regulation, influencing gene expression and cellular processes. Phosphorylation of HDAC4 at serine 632 has been linked to its activity and function in various cellular pathways, making this antibody essential for studying the role of HDAC4 phosphorylation in biological processes such as cell differentiation, proliferation, and gene transcription.
By targeting the phosphorylated form of HDAC4, researchers can gain insights into the complex regulation of this important protein and its impact on health and disease. The Phospho-HDAC4 (S632) Polyclonal Antibody is an essential tool for investigating the mechanisms underlying HDAC4 function and its potential as a therapeutic target in conditions such as cancer, neurological disorders, and cardiovascular diseases.
Product Name:
Phospho-HDAC4-S632 Rabbit Polyclonal Antibody
SKU:
CABP0359
Size:
100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A phospho specific peptide corresponding to residues surrounding S632 of human HDAC4
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.
Purification Method:
Affinity purification
Gene ID:
9759
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from 293 cells using Phospho-HDAC4-S632 Rabbit pAb (CABP0359).Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% BSA.
