Phospho-GSK3β-Y216 + GSK3α-Y279 Rabbit Polyclonal Antibody (CABP0512)
- SKU:
- CABP0512
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
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Description
Product Name: | Phospho-GSK3β-Y216 + GSK3α-Y279 Rabbit Polyclonal Antibody |
SKU: | CABP0512 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic phosphorylated peptide around Y216 of human GSK3β (NP_001139628). |
Sequence: | VSYI C |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | GSK3B; gsk-3β; Phospho-GSK3β-Y216 + GSK3α-Y279 |
Positive Sample: | 293 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm, Nucleus. |
Calculated MW: | 47kDa |
Observed MW: | 50kDa |
The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 2931/2932 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |