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Phospho-GSK3α-S21+GSK3β-S9 Monoclonal Antibody (CABP1341)

SKU:
CABP1341
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
€139 - €609
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Phospho-GSK3α-S21+GSK3β-S9 Monoclonal Antibody
SKU:CABP1341
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Mouse
Immunogen:A synthetic phosphorylated peptide around S21&S9 of human GSK3α/GSK3β (NP_063937.2/NP_002084.2).
Sequence:TSSF A
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:GSK3B; GSK 3 beta; GSK3A; GSK 3 alpha; Phospho-GSK3α-S21+GSK3β-S9
Positive Sample:NIH/3T3+FBS
Conjugate:Unconjugated
Cellular Localization:Cell membrane, Cytoplasm, Nucleus.
Calculated MW:51kDa/46kDa
Observed MW:51kDa/46kDa

The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Purification Method:Affinity purification
Gene ID:2931/2932
Clone Number:ARC54771
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of NIH/3T3, using Phospho-GSK3α-S21+GSK3β-S9 antibody (CABP1341) at 1:800 dilution.NIH/3T3 cells were treated by 10% FBS at 37℃ for 30 minutes after serum-starvation overnight.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.

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