The Phospho-GRIA1 (S849) Polyclonal Antibody (CABP0242) is a valuable tool for researchers studying the phosphorylation of Glutamate Receptor 1 (GRIA1), a key player in excitatory neurotransmission in the brain. This antibody, raised in rabbits, is specifically designed to target the phosphorylated form of GRIA1 at Serine 849 and is highly reactive with human samples.Validated for use in Western blot applications, the Phospho-GRIA1 (S849) Polyclonal Antibody enables the detection and analysis of phosphorylated GRIA1 in various cell types and tissues. Its specificity for the phosphorylated form of GRIA1 makes it an essential tool for investigating the role of GRIA1 phosphorylation in neurological disorders, synaptic plasticity, and cognitive function.
By understanding the phosphorylation of GRIA1 at Serine 849, researchers can gain insights into the mechanisms underlying synaptic transmission and plasticity, offering new avenues for the development of therapeutics targeting neurological conditions such as Alzheimer's disease, epilepsy, and mood disorders. Invest in the Phospho-GRIA1 (S849) Polyclonal Antibody for your research into excitatory neurotransmission and synaptic function.
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
2890
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts from rat brain tissue using Phospho-GluR1/GRIA1-S849 antibody (CABP0242).Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% BSA.
