Phospho-GCN2-T899 Monoclonal Antibody (CABP1356)
- SKU:
- CABP1356
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Frequently bought together:
Description
Product Name: | Phospho-GCN2-T899 Monoclonal Antibody |
SKU: | CABP1356 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic phosphorylated peptide around T899 of human Phospho-GCN2-T899 (NP_001013725.2). |
Sequence: | HLTG M |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 |
Synonyms: | GCN2; PVOD2; Phospho-GCN2-T899 |
Positive Sample: | HeLa+Calyculin A |
Conjugate: | Unconjugated |
Cellular Localization: | Cytosol, Cytosolic ribosome |
Calculated MW: | 187kDa |
Observed MW: | 220kDa |
This gene encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the downregulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2.
Purification Method: | Affinity purification |
Gene ID: | 440275 |
Clone Number: | ARC57177 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |