The Phospho-GATA1 (S310) Polyclonal Antibody (CABP0354) is specifically designed for researchers studying GATA1, a transcription factor essential for erythroid and megakaryocytic cell differentiation. This antibody, produced in rabbits, has high specificity for human samples and is validated for use in Western blot applications. By binding to the phosphorylated form of GATA1 at serine 310, this antibody enables the detection and analysis of GATA1 activity in various cellular contexts, making it an invaluable tool for studies in hematology and cancer research.
GATA1 is a key regulator of hematopoiesis, playing a crucial role in the development and function of red blood cells and platelets. Phosphorylation at serine 310 has been linked to the modulation of GATA1 activity and target gene expression, making it a critical site for investigating the regulatory mechanisms of this transcription factor. Understanding the role of phosphorylated GATA1 in normal and diseased tissues is important for unraveling the complexity of hematopoietic disorders and identifying potential therapeutic targets for blood-related diseases.
Product Name:
Phospho-GATA1-S310 Rabbit Polyclonal Antibody
SKU:
CABP0354
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A phospho specific peptide corresponding to residues surrounding S310 of human GATA1
This gene encodes a protein which belongs to the GATA family of transcription factors. The protein plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia.
Purification Method:
Affinity purification
Gene ID:
2623
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts from K-562 cells, using Phospho-GATA1-S310 antibody (CABP0354).Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% BSA.
