The Phospho-Fyn (Y416)/Lck (Y416) Polyclonal Antibody (CABP0511) is a valuable tool for researchers studying protein phosphorylation events in immune signaling pathways. This antibody, raised in rabbits, specifically targets phosphorylated Y416 residues on Fyn and Lck proteins, key regulators of T-cell activation and immune response.By detecting and analyzing the phosphorylation status of Fyn and Lck, researchers can gain insights into the activation and regulation of T-cell signaling, which is essential for understanding immune responses in various diseases, including autoimmune disorders and cancer.
This antibody is validated for Western blot applications and is highly reactive with human samples, making it a reliable choice for immunology and cancer research studies.The Phospho-Fyn (Y416)/Lck (Y416) Polyclonal Antibody (CABP0511) is a crucial tool for investigating the intricate mechanisms of immune regulation and T-cell activation, providing valuable insights that can contribute to the development of new therapies for immune-related diseases.
This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist. [provided by RefSeq, Jul 2008]
Purification Method:
Affinity purification
Gene ID:
2534/3055/3932/4067/6714/7525
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of NIH3T3 cells, using Phospho-SRC Family-Y416 antibody (CABP0511).Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% BSA.
