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Phospho-EZR-T567/RDX-T564/MSN-T558 Rabbit Polyclonal Antibody (CABP1121)

SKU:
CABP1121
Product Type:
Antibody
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
$503
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Phospho-EZR-T567/RDX-T564/MSN-T558 Rabbit Polyclonal Antibody
SKU:CABP1121
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Rat
Immunogen:A synthetic phosphorylated peptide around T567 of human EZR/RDX/MSNEZR (NP_003370.2).
Sequence:YKTL R
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:2000
Positive Sample:PC-12
Observed MW:80kDa

The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.

Purification Method:Affinity purification
Gene ID:7430/4478/5962
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from PC-12 cells, using Phospho-EZR-T567/RDX-T564/MSN-T558 Rabbit pAb (CABP1121) at 1:1000 dilution.PC-12 cells were treated by ATP(5 mM) at 30℃ for 1 hour.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% BSA.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.

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