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Phospho-EZH2/KMT6-T311 Polyclonal Antibody (CABP1269)

SKU:
CABP1269
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
€179 - €469
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Phospho-EZH2/KMT6-T311 Polyclonal Antibody
SKU:CABP1269
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Rat
Immunogen:A synthetic phosphorylated peptide around T311 of human EZH2/KMT6 (NP_001190176.1).
Sequence:KNTE T
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:WVS; ENX1; KMT6; WVS2; ENX-1; EZH2b; KMT6A; Phospho-EZH2/KMT6-T311
Positive Sample:C6
Conjugate:Unconjugated
Cellular Localization:Nucleus.
Calculated MW:85kDa
Observed MW:98kDa

This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene.

Purification Method:Affinity purification
Gene ID:2146
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of C6 cells, using Phospho-EZH2/KMT6-T311 antibody (CABP1269) at 1:1000 dilution.C6 cells were treated by AICAR (0.5 mM) at 37℃ for 30 minutes after serum-starvation overnight.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 60s.

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