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Estrogen Receptor beta Rabbit Polyclonal Antibody (CAB2546)

SKU:
CAB2546
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Epigenetics and Nuclear Signaling
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Estrogen Receptor beta Rabbit Polyclonal Antibody
SKU:CAB2546
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-153 of human Estrogen Receptor beta (NP_001428.1).
Sequence:MDIK NSPS SLNS PSSY NCSQ SILP LEHG SIYI PSSY VDSH HEYP AMTF YSPA VMNY SIPS NVTN LEGG PGRQ TTSP NVLW PTPG HLSP LVVH RQLS HLYA EPQK SPWC EARS LEHT LPVN RETL KRKV SGNR CASP VTGP GSKR DAHF CAVC S
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:Erb; ESRB; ODG8; ESTRB; NR3A2; ER-BETA; ESR-BETA; Estrogen Receptor beta
Positive Sample:Daudi
Conjugate:Unconjugated
Cellular Localization:Nucleus.
Calculated MW:59kDa
Observed MW:60kDa

This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized.

Purification Method:Affinity purification
Gene ID:2100
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from Daudi cells using Estrogen Receptor beta Rabbit pAb(CAB2546) at 1:600 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25 μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.

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