ERBB2IP Rabbit Polyclonal Antibody (CAB8585)
- SKU:
- CAB8585
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | ERBB2IP Rabbit Polyclonal Antibody |
SKU: | CAB8585 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1152-1371 of human ERBB2IP (NP_061165.1). |
Sequence: | IPER TMSV SDFN YSRT SPSK RPNA RVGS EHSL LDPP GKSK VPRD WREQ VLRH IEAK KLEK MPLS NGQM GQPL RPQA NYSQ IHHP PQAS VARH PSRE QLID YLML KVAH QPPY TQPH CSPR QGHE LAKQ EIRV RVEK DPEL GFSI SGGV GGRG NPFR PDDD GIFV TRVQ PEGP ASKL LQPG DKII QANG YSFI NIEH GQAV SLLK TFQN TVEL IIVR EVSS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | LAP2; ERBB2IP; HEL-S-78 |
Positive Sample: | 293T,HepG2 |
Conjugate: | Unconjugated |
Cellular Localization: | Basolateral cell membrane, Cell junction, Nucleus membrane, hemidesmosome. |
Calculated MW: | 158kDa |
Observed MW: | 182kDa |
This gene is a member of the leucine-rich repeat and PDZ domain (LAP) family. The encoded protein contains 17 leucine-rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization. It has also been shown to affect the Ras signaling pathway by disrupting Ras-Raf interaction. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method: | Affinity purification |
Gene ID: | 55914 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |