Phospho-eIF4E-S209 Monoclonal Antibody (CABP1024)
- SKU:
- CABP1024
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Applications:
- WB
- Isotype:
- IgG
- Host Species:
- Rabbit
Frequently bought together:
Description
Product Name: | Phospho-eIF4E-S209 Monoclonal Antibody |
SKU: | CABP1024 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Rat |
Immunogen: | A phospho specific peptide corresponding to residues surrounding S209 of human Phospho-eIF4E-S209 (NP_001959.1). |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 |
Synonyms: | CBP; EIF4F; AUTS19; EIF4E1; eIF-4E; EIF4EL1; Phospho-eIF4E-S209 |
Positive Sample: | HeLa FBS |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, P-body, Cytoplasm, Cytoplasm, Stress granule, Cytosol, Nucleus |
Calculated MW: | 25kDa |
Observed MW: | 25kDa |
The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 1977 |
Clone Number: | ARC1569 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |