Phospho-eIF4E-S209 Rabbit Polyclonal Antibody (CABP0747)
- SKU:
- CABP0747
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | Phospho-eIF4E-S209 Rabbit Polyclonal Antibody |
SKU: | CABP0747 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | A synthetic phosphorylated peptide around S209 of human eIF4E (NP_001959.1). |
Sequence: | SGST T |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:100 - 1:500 |
Synonyms: | CBP; EIF4F; AUTS19; EIF4E1; eIF-4E; EIF4EL1; Phospho-eIF4E-S209 |
Positive Sample: | HT-29,NIH/3T3 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, P-body. |
Calculated MW: | 25kDa |
Observed MW: | 25kDa |
The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 1977 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |