eIF4E Rabbit Polyclonal Antibody (CAB0468)
- SKU:
- CAB0468
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | eIF4E Rabbit Polyclonal Antibody |
SKU: | CAB0468 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-217 of human eIF4E (NP_001959.1). |
Sequence: | MATV EPET TPTP NPPT TEEE KTES NQEV ANPE HYIK HPLQ NRWA LWFF KNDK SKTW QANL RLIS KFDT VEDF WALY NHIQ LSSN LMPG CDYS LFKD GIEP MWED EKNK RGGR WLIT LNKQ QRRS DLDR FWLE TLLC LIGE SFDD YSDD VCGA VVNV RAKG DKIA IWTT ECEN REAV THIG RVYK ERLG LPPK IVIG YQSH ADTA TKSG STTK NRFV V |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | CBP; EIF4F; AUTS19; EIF4E1; eIF-4E; EIF4EL1; eIF4E |
Positive Sample: | MCF7,293T |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, P-body. |
Calculated MW: | 25kDa |
Observed MW: | 24kDa |
The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 1977 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |