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Anti-Phospho-eIF4B-S406 pAb Antibody (CABP0782)

SKU:
CABP0782
Product Type:
Antibody
Applications:
WB
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Metabolism
€129 - €489
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-Phospho-eIF4B-S406 Antibody
Antibody SKU:CABP0782
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:A synthetic phosphorylated peptide around S406 of human eIF4B (NP_001408.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:
Immunogen:A synthetic phosphorylated peptide around S406 of human eIF4B (NP_001408.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:HPSW R
Gene ID:1975
Uniprot:P23588
Cellular Location:
Calculated MW:64kDa/69kDa
Observed MW:Refer to Figures
Synonyms:EIF4B, EIF-4B, PRO1843
Background:Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.
UniProt Protein Function:EIF4B: eukaryotic translation initiation factor 4B. Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.
UniProt Protein Details:

Protein type:RNA-binding; Translation initiation; Translation

Chromosomal Location of Human Ortholog: 12q13.13

Cellular Component: cytosol; eukaryotic translation initiation factor 4F complex; polysome

Molecular Function:helicase activity; protein binding; ribosomal small subunit binding; RNA binding; RNA strand annealing activity; RNA strand-exchange activity

Biological Process: formation of translation preinitiation complex; poly(A) tail shortening; regulation of translational initiation; translational initiation

UniProt Code:P23588
NCBI GenInfo Identifier:205371761
NCBI Gene ID:1975
NCBI Accession:P23588.2
UniProt Secondary Accession:P23588,Q4G0E3, Q53HQ2, Q6GPH5, Q6IB46, Q8WYK5, B4DS13
UniProt Related Accession:P23588
Molecular Weight:64,805 Da
NCBI Full Name:Eukaryotic translation initiation factor 4B
NCBI Synonym Full Names:eukaryotic translation initiation factor 4B
NCBI Official Symbol:EIF4B  
NCBI Official Synonym Symbols:EIF-4B; PRO1843  
NCBI Protein Information:eukaryotic translation initiation factor 4B
UniProt Protein Name:Eukaryotic translation initiation factor 4B
Protein Family:Eukaryotic translation initiation factor
UniProt Gene Name:EIF4B  
UniProt Entry Name:IF4B_HUMAN

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