Phospho-EFNB1/EFNB2 (Y330) Antibody (PACO00276)
- SKU:
- PACO00276
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
Phospho-EFNB1/EFNB2 (Y330) Antibody (PACO00276)
The Phospho-EFNB1/EFNB2 (Y330) Antibody (PACO00276) is a valuable tool for researchers studying the phosphorylation of EFNB1 and EFNB2 proteins. This antibody, raised in rabbits, is highly specific and reactive with human samples. It is validated for use in Western blot applications, enabling the detection and analysis of phosphorylated EFNB1 and EFNB2 in various cell types.EFNB1 and EFNB2 are members of the Ephrin family of cell surface proteins involved in cell-to-cell communication and signaling. Phosphorylation of these proteins at the Y330 site plays a crucial role in regulating their function and downstream signaling pathways.
Understanding the phosphorylation status of EFNB1 and EFNB2 is essential for elucidating their roles in processes such as development, tissue regeneration, and disease progression.Researchers in the fields of signal transduction, developmental biology, and cancer biology will find this antibody to be a valuable asset in their studies. By enabling the specific detection of phosphorylated EFNB1 and EFNB2, the PACO00276 antibody opens up new possibilities for unraveling the intricate mechanisms by which these proteins contribute to cellular functions and disease processes.
| Antibody Name: | Phospho-EFNB1/EFNB2 (Y330) Antibody |
| Antibody SKU: | PACO00276 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | WB:1:500-1:2000 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | synthesized peptide derived from human Ephrin-B1/2 around the phosphorylation site of Y330. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | EFNB1; EFL3; EPLG2; LERK2; Ephrin-B1; EFL-3; ELK ligand; ELK-L; EPH-related receptor tyrosine kinase ligand 2; LERK-2; EFNB2; EPLG5; HTKL; LERK5; Ephrin-B2; EPH-related receptor tyrosine kinase ligand 5; LERK-5; HTK ligand; HTK-L |
| UniProt Protein Function: | EFNB1: a type I membrane protein of the ephrin family. A ligand of Eph-related receptor tyrosine kinases EphB1 and EphA1. Ephrins and ephrin receptors mediate numerous developmental processes, particularly in the nervous system. Ephrin-B1 may play a role in cell adhesion and functions in the development or maintenance of the nervous system. Binding to its receptor induces the collapse of commissural axons/growth cones in vitro. Induced by TNF-alpha. Expressed in brain, heart, placenta, lung, liver, skeletal muscle, kidney, and pancreas. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Ligand, receptor tyrosine kinase Chromosomal Location of Human Ortholog: Xq12 Cellular Component: integral to plasma membrane; cytoplasm; plasma membrane; synapse; nucleus; lipid raft Molecular Function:protein binding; ephrin receptor binding Biological Process: axon guidance; cell-cell signaling; ephrin receptor signaling pathway; positive regulation of T cell proliferation; cell adhesion; embryonic pattern specification; neural crest cell migration Disease: Craniofrontonasal Syndrome |
| NCBI Summary: | The protein encoded by this gene is a type I membrane protein and a ligand of Eph-related receptor tyrosine kinases. It may play a role in cell adhesion and function in the development or maintenance of the nervous system. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P98172 |
| NCBI GenInfo Identifier: | 1706668 |
| NCBI Gene ID: | 1947 |
| NCBI Accession: | P98172.1 |
| UniProt Secondary Accession: | P98172,D3DVU0, |
| UniProt Related Accession: | P98172 |
| Molecular Weight: | 346 |
| NCBI Full Name: | Ephrin-B1 |
| NCBI Synonym Full Names: | ephrin-B1 |
| NCBI Official Symbol: | EFNB1Â Â |
| NCBI Official Synonym Symbols: | CFND; CFNS; EFB1; EFL3; EPLG2; Elk-L; LERK2Â Â |
| NCBI Protein Information: | ephrin-B1; EFL-3; LERK-2; ELK ligand; ligand of eph-related kinase 2; eph-related receptor tyrosine kinase ligand 2 |
| UniProt Protein Name: | Ephrin-B1 |
| UniProt Synonym Protein Names: | EFL-3; ELK ligand; ELK-L; EPH-related receptor tyrosine kinase ligand 2; LERK-2 |
| Protein Family: | Ephrin |
| UniProt Gene Name: | EFNB1Â Â |
| UniProt Entry Name: | EFNB1_HUMAN |
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