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[KO Validated] EEF2K Rabbit Polyclonal Antibody (CAB5404)

SKU:
CAB5404
Product Type:
Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
  • KO Validated Antibodies 1 Anti-EEF2K Antibody CAB5404KO Validated
  • KO Validated Antibodies 1 Anti-EEF2K Antibody CAB5404KO Validated
  • KO Validated Antibodies 1 Anti-EEF2K Antibody CAB5404KO Validated
€139 - €419
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Description

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Product Name:[KO Validated] EEF2K Rabbit Polyclonal Antibody
SKU:CAB5404
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 406-725 of human EEF2K (NP_037434.1).
Sequence:KLDH LHWP VFSD LDNM ASRD HDHL DNHR ESEN SGDS GYPS EKRG ELDD PEPR EHGH SYSN RKYE SDED SLGS SGRV CVEK WNLL NSSR LHLP RASA VALE VQRL NALD LEKK IGKS ILGK VHLA MVRY HEGG RFCE KGEE WDQE SAVF HLEH AANL GELE AIVG LGLM YSQL PHHI LADV SLKE TEEN KTKG FDYL LKAA EAGD RQSM ILVA RAFD SGQN LSPD RCQD WLEA LHWY NTAL EMTD CDEG GEYD GMQD EPRY MMLA REAE MLFT GGYG LEKD PQRS GDLY TQAA EAAM EAMK GRLA NQYY QKAE EAWA QMEE
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200
Synonyms:eEF-2K; CaMKIII; HSU93850; 2K
Positive Sample:HepG2,HeLa,LOVO,22Rv1,293T,Mouse spleen
Conjugate:Unconjugated
Cellular Localization:cytoplasm, cytosol, dendritic spine, glutamatergic synapse, postsynaptic density
Calculated MW:82kDa
Observed MW:110kDa

This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment.

Purification Method:Affinity purification
Gene ID:29904
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various cell lines, using EEF2K antibody (CAB5404) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 40s.

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