The Phospho-DLG2 (Y340) Rabbit Polyclonal Antibody (CABP1080) is a valuable tool for researchers studying DLG2 phosphorylation, a process that plays a crucial role in neuronal development and synaptic plasticity. This antibody, raised in rabbits, is highly specific for phosphorylated DLG2 at tyrosine 340 and is validated for use in various applications, including Western blot and immunohistochemistry.DLG2, also known as PSD-93, is a scaffold protein that interacts with NMDA receptors and other synaptic proteins to regulate synaptic transmission and plasticity. Phosphorylation of DLG2 at tyrosine 340 has been linked to changes in synaptic strength and neuronal activity, making it essential for understanding the molecular mechanisms underlying learning and memory.
This antibody is an invaluable tool for researchers investigating the role of DLG2 phosphorylation in neuronal signaling, synaptic plasticity, and neurological disorders. Its high specificity and sensitivity make it an ideal choice for studies in neuroscience, neurobiology, and pharmacology. Unlock the potential of your research with the Phospho-DLG2 (Y340) Rabbit Polyclonal Antibody (CABP1080).
This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. The encoded protein forms a heterodimer with a related family member that may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Multiple transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described, but their full-length nature is not known.
Purification Method:
Affinity purification
Gene ID:
1740
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using Phospho-PSD93/chapsyn-110/DLG2-Y340 Rabbit pAb (CABP1080) at 1:1000 dilution.293T cells were treated by ATP(5 mM) at 30℃ for 1 hour.NIH/3T3 cells were treated by ATP(5 mM) at 30℃ for 1 hour.C6 cells were treated by ATP(5 mM) at 30℃ for 1 hour.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% BSA.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
