DDX3X Rabbit Polyclonal Antibody (CAB5637)
- SKU:
- CAB5637
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Description
Product Name: | DDX3X Rabbit Polyclonal Antibody |
SKU: | CAB5637 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human DDX3X (NP_001347.3). |
Sequence: | MSHV AVEN ALGL DQQF AGLD LNSS DNQS GGST ASKG RYIP PHLR NREA TKGF YDKD SSGW SSSK DKDA YSSF GSRS DSRG KSSF FSDR GSGS RGRF DDRG |
Tested Applications: | WB IHC-P IF/ICC IP ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 300μg-600μg extracts of whole cells |
Synonyms: | DBX; DDX3; HLP2; DDX14; CAP-Rf; MRX102; MRXSSB; DDX3X |
Positive Sample: | Mouse brain,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Mitochondrion outer membrane, Nucleus speckle. |
Calculated MW: | 73kDa |
Observed MW: | 75kDa |
The protein encoded by this gene is a member of the large DEAD-box protein family, that is defined by the presence of the conserved Asp-Glu-Ala-Asp (DEAD) motif, and has ATP-dependent RNA helicase activity. This protein has been reported to display a high level of RNA-independent ATPase activity, and unlike most DEAD-box helicases, the ATPase activity is thought to be stimulated by both RNA and DNA. This protein has multiple conserved domains and is thought to play roles in both the nucleus and cytoplasm. Nuclear roles include transcriptional regulation, mRNP assembly, pre-mRNA splicing, and mRNA export. In the cytoplasm, this protein is thought to be involved in translation, cellular signaling, and viral replication. Misregulation of this gene has been implicated in tumorigenesis. This gene has a paralog located in the nonrecombining region of the Y chromosome. Pseudogenes sharing similarity to both this gene and the DDX3Y paralog are found on chromosome 4 and the X chromosome. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 1654 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |