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Phospho-CSNK1G1/CSNK1G2/CSNK1G3 (Y263) Antibody (PACO04623)

SKU:
PACO04623
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
IHC
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€269
Frequently bought together:

Description

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Phospho-CSNK1G1/CSNK1G2/CSNK1G3 (Y263) Antibody (PACO04623)

The Phospho-CSNK1G1/CSNK1G2/CSNK1G3 (Y263) Antibody (PAC04623) is a highly specific and sensitive tool for researchers studying the phosphorylation of CSNK1G1, CSNK1G2, and CSNK1G3 proteins. This antibody, raised in rabbits, is especially reactive with human samples and has been validated for use in Western blot applications. By binding to the phosphorylated form of these proteins at tyrosine 263, researchers can detect and analyze their activity in various cell types.The CSNK1G1, CSNK1G2, and CSNK1G3 proteins are key regulators of multiple cellular processes, including cell proliferation, differentiation, and apoptosis. Phosphorylation of these proteins at tyrosine 263 is known to be important for their function and regulation, making this antibody an essential tool for studies in cell signaling, cancer biology, and developmental biology.

With its high specificity and sensitivity, the Phospho-CSNK1G1/CSNK1G2/CSNK1G3 (Y263) Antibody (PAC04623) is ideal for researchers looking to deepen their understanding of the role of protein phosphorylation in cellular processes and disease pathways. Its use can provide valuable insights into the molecular mechanisms underlying various physiological and pathological conditions, paving the way for the development of targeted therapies and treatment strategies.

Antibody Name:Phospho-CSNK1G1/CSNK1G2/CSNK1G3 (Y263) Antibody
Antibody SKU:PACO04623
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA, IHC
Recommended Dilutions:IHC:1:100-1:300
Species Reactivity:Human, Mouse, Rat
Immunogen:synthesized peptide derived from human Casein Kinase Igamma1/2/3 around the phosphorylation site of Y263.
Form:Liquid
Storage Buffer:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:CSNK1G1; Casein kinase I isoform gamma-1; CKI-gamma 1; CSNK1G2; CK1G2; Casein kinase I isoform gamma-2; CKI-gamma 2; CSNK1G3; Casein kinase I isoform gamma-3; CKI-gamma 3
UniProt Protein Function:CK1G1: an ubiquitous protein kinase of the CK1 family. Involved in growth and morphogenesis. Two splice variant isoforms have been described.
UniProt Protein Details:

Protein type:EC 2.7.11.1; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; Protein kinase, CK1; CK1 group; CK1 family

Chromosomal Location of Human Ortholog: 15q22.1-q22.31

Cellular Component: cytoplasm; nucleus

Molecular Function:protein serine/threonine kinase activity; ATP binding

Biological Process: regulation of cell shape; peptidyl-serine phosphorylation; Wnt receptor signaling pathway; endocytosis

NCBI Summary:This gene encodes a member of the casein kinase I gene family. The encoded protein is a serine/threonine kinase that phosphorylates acidic proteins, and participates in pathways for cell growth. [provided by RefSeq, Nov 2011]
UniProt Code:Q9HCP0
NCBI GenInfo Identifier:18202957
NCBI Gene ID:53944
NCBI Accession:Q9HCP0.1
UniProt Secondary Accession:Q9HCP0,Q5JPH1, Q96AE9, Q9HCP1,
UniProt Related Accession:Q9HCP0
Molecular Weight:422
NCBI Full Name:Casein kinase I isoform gamma-1
NCBI Synonym Full Names:casein kinase 1, gamma 1
NCBI Official Symbol:CSNK1G1  
NCBI Official Synonym Symbols:CK1gamma1  
NCBI Protein Information:casein kinase I isoform gamma-1; CKI-gamma 1
UniProt Protein Name:Casein kinase I isoform gamma-1
Protein Family:Casein kinase
UniProt Gene Name:CSNK1G1  
UniProt Entry Name:KC1G1_HUMAN

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