Phospho-CRKL-Y207 Rabbit Polyclonal Antibody (CABP0824)
- SKU:
- CABP0824
- Product Type:
- Antibody
- Applications:
- WB
- IHC
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | Phospho-CRKL-Y207 Rabbit Polyclonal Antibody |
SKU: | CABP0824 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic phosphorylated peptide around Y207 of human CRKL (NP_005198.1). |
Sequence: | HAYA Q |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:100 |
Synonyms: | CRKL; Phospho-CRKL-Y207 |
Positive Sample: | K-562 |
Conjugate: | Unconjugated |
Cellular Localization: | cytosol, extrinsic component of postsynaptic membrane, neuromuscular junction, nucleoplasm |
Calculated MW: | 34kDa |
Observed MW: | 38kDa |
This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.
Purification Method: | Affinity purification |
Gene ID: | 1399 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |