Phospho-CFL1-Y139 Polyclonal Antibody (CABP0330)
- SKU:
- CABP0330
- Product Type:
- Antibody
- Applications:
- IHC
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | Phospho-CFL1-Y139 Polyclonal Antibody |
SKU: | CABP0330 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic phosphorylated peptide around Y139 of human Phospho-CFL1-Y139 (NP_005498.1). |
Sequence: | ANCY E |
Tested Applications: | IHC-P ELISA |
Recommended Dilution: | IHC-P,1:50 - 1:200 |
Synonyms: | CFL; cofilin; HEL-S-15; Phospho-CFL1-Y139 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell projection, Cytoplasm, Cytoplasmic side, Nucleus matrix, Peripheral membrane protein, cytoskeleton, lamellipodium membrane, ruffle membrane. |
Calculated MW: | 19kDa |
Observed MW: | Refer to figures |
The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.
Purification Method: | Affinity purification |
Gene ID: | 1072 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |