The Phospho-CDK2 (T160) Polyclonal Antibody (CABP0325) from AssayGenie is a valuable tool for researchers studying cell cycle regulation and proliferation. This antibody is raised in rabbits and specifically targets the phosphorylated form of CDK2 at threonine 160, allowing for detection and analysis in various cell types.CDK2 is a key regulator of cell cycle progression, with phosphorylation at threonine 160 playing an important role in its activity. By targeting this specific phosphorylation site, researchers can gain insights into the mechanisms underlying cell cycle control and potentially identify novel therapeutic targets for diseases like cancer.
The Phospho-CDK2 (T160) Polyclonal Antibody is validated for use in Western blot applications and is highly reactive with human samples. Its versatility and specificity make it an ideal tool for studies in cell biology, cancer research, and drug discovery. Gain a deeper understanding of CDK2 regulation with this high-quality antibody from AssayGenie.
Product Name:
Phospho-CDK2-T160 Rabbit Polyclonal Antibody
SKU:
CABP0325
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic phosphorylated peptide around T160 of human CDK2 (NP_001789.2?/NP_001249.1).
This gene encodes a member of a family of serine/threonine protein kinases that participate in cell cycle regulation. The encoded protein is the catalytic subunit of the cyclin-dependent protein kinase complex, which regulates progression through the cell cycle. Activity of this protein is especially critical during the G1 to S phase transition. This protein associates with and regulated by other subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A), and p27Kip1 (CDKN1B). Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
1017
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from C6 cells, using Phospho-CDK2-T160 Rabbit pAb (CABP0325) at 1:400 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
