CCDC88A Rabbit Polyclonal Antibody (CAB16132)
- SKU:
- CAB16132
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | CCDC88A Rabbit Polyclonal Antibody |
SKU: | CAB16132 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1571-1870 of human CCDC88A (NP_001129069.1). |
Sequence: | DDSS TGSR VHAS RPAS LDSG RTST SNSN NNAS LHEV KAGA VNNQ SRPQ SHSS GEFS LLHD HEAW SSSG SSPI QYLK RQTR SSPV LQHK ISET LESR HHKI KTGS PGSE VVTL QQFL EESN KLTS VQIK SSSQ ENLL DEVM KSLS VSSD FLGK DKPV SCGL ARSV SGKT PGDF YDRR TTKP EFLR PGPR KTED TYFI SSAG KPTP GTQG KIKL VKES SLSR QSKD SNPY ATLP RASS VIST AEGT TRRT SIHD FLTK DSRL PISV DSPP AAAD SNTT AASN VDKV QESR NSKS RSRE QQSS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | APE; GIV; GRDN; PEHO; HkRP1; PEHOL; GIRDIN; KIAA1212; CCDC88A |
Positive Sample: | U-87MG,LO2 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cell projection, Cytoplasm, Cytoplasmic vesicle, Membrane, cytosol, lamellipodium |
Calculated MW: | 216kDa |
Observed MW: | 220kDa |
This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method: | Affinity purification |
Gene ID: | 55704 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |