Phospho-Caveolin-1-Y14 Rabbit Polyclonal Antibody (CABP0742)
- SKU:
- CABP0742
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | Phospho-Caveolin-1-Y14 Rabbit Polyclonal Antibody |
SKU: | CABP0742 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | A synthetic phosphorylated peptide around Y14 of human Caveolin-1 (NP_001744.2). |
Sequence: | HLYT V |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:2000 |
Synonyms: | CGL3; PPH3; BSCL3; LCCNS; VIP21; MSTP085; Phospho-Caveolin-1-Y14 |
Positive Sample: | HeLa,NIH/3T3 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Golgi apparatus membrane, Membrane, Membrane raft, Peripheral membrane protein, caveola. |
Calculated MW: | 20kDa |
Observed MW: | 23kDa |
The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.
Purification Method: | Affinity purification |
Gene ID: | 857 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |