Phospho-Camk2a-T286 Rabbit Polyclonal Antibody (CABP0255)
- SKU:
- CABP0255
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | Phospho-Camk2a-T286 Rabbit Polyclonal Antibody |
SKU: | CABP0255 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic phosphorylated peptide around T286 of human Camk2a (NP_741960.1). |
Sequence: | QETV D |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:2000 - 1:4000 |
Synonyms: | CAMKA; MRD53; MRT63; CaMKIIalpha; CaMKIINalpha; Phospho-Camk2a-T286 |
Positive Sample: | Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, presynaptic cell membrane, synapse. |
Calculated MW: | 54kDa |
Observed MW: | 50kDa |
The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Several transcript variants encoding distinct isoforms have been identified for this gene.
Purification Method: | Affinity purification |
Gene ID: | 815 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |