Phospho-Camk2-T286 Monoclonal Antibody (CABP1386)
- SKU:
- CABP1386
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Frequently bought together:
Description
Product Name: | Phospho-Camk2-T286 Monoclonal Antibody |
SKU: | CABP1386 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | A synthetic phosphorylated peptide around T286 of human Camk2. |
Sequence: | QETV D |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:2000 - 1:10000 |
Synonyms: | CAMKA; MRD53; MRT63; CaMKIIalpha; CaMKIINalpha; CAM2; CAMK2; CAMKB; MRD54; CaMKIIbeta; CAMKD; CAMK; CAMKG; MRD59; CAMK-II; Phospho-Camk2-T286 |
Positive Sample: | Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Presynaptic cell membrane, Synapse. |
Calculated MW: | 54kDa |
Observed MW: | 50kDa |
The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2 )/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Several transcript variants encoding distinct isoforms have been identified for this gene.
Purification Method: | Affinity purification |
Gene ID: | 816/817/818/815 |
Clone Number: | ARC57709 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |