Caldesmon Rabbit Monoclonal Antibody (CAB4884)
- SKU:
- CAB4884
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- CDM
- H-CAD
- HCAD
- L-CAD
- LCAD
- NAG22
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | Caldesmon Rabbit Monoclonal Antibody |
SKU: | CAB4884 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 694-793 of human Caldesmon (Q05682). |
Sequence: | PTKP AASD LPVP AEGV RNIK SMWE KGNV FSSP TAAG TPNK ETAG LKVG VSSR INEW LTKT PDGN KSPA PKPS DLRP GDVS SKRN LWEK QSVD KVTS PTKV |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | CDM; HCAD; LCAD; h-CD; H-CAD; L-CAD; NAG22; Caldesmon |
Positive Sample: | HeLa |
Conjugate: | Unconjugated |
Cellular Localization: | Actin cytoskeleton, cytoskeleton, cytosol, plasma membrane |
Calculated MW: | 93kDa |
Observed MW: | 80kDa |
This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
Purification Method: | Affinity purification |
Gene ID: | 800 |
Clone Number: | ARC0315 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |