Phospho-c-Jun (Ser73) In-Cell ELISA- High Sensitivity

Phospho-c-Jun (Ser73) In-Cell ELISA

SKU:

CBCAB01510

Product Type:

ELISA Kit

ELISA Type:

Cell Based Phospho Specific

Research Area:

Epigenetics and Nuclear Signaling

Reactivity:

Human

Mouse

Rat

Detection Method:

Colorimetric

Description

Description

MSDS

Phospho-c-Jun (Ser73) Cell-Based ELISA

Product Description:	The Phospho-c-Jun (Ser73) Colorimetric Cell-Based ELISA Kit allows for qualitative detection of Phospho-c-Jun(Ser73) in plated and fixed cells.
Target Synonyms:	Activator protein 1; AH119; AP-1; AP1; c-Jun; Jun A; p39; Proto-oncogene c-jun; RJG-9; V-jun avian sarcoma virus 17 oncogene homolog
Detection Target:	Phospho-IRAK1(Thr209)
Reactivity:	H:S73, M:S73, R:S73
Pack Size:	2 x 96 assays
Detection Method:	Colorimetric 450 nm
Format:	Cell-Based ELISA/In-Cell ELISA
Storage and Stability Guarantee:	4 °C/6 Months
Sample Type:	Plated & fixed cells
Range:	5000 cells/well minimum
Time:	4.5 hours

Phospho-c-Jun (Ser73) Cell-Based ELISA Protein Information

UniProt Protein Function:	Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells (PubMed:24623306). Binds to the USP28 promoter in colorectal cancer (CRC) cells (PubMed:24623306).
NCBI Summary:	This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies. [provided by RefSeq, Jul 2008]
UniProt Code:	P05412
NCBI GenInfo Identifier:	135298
NCBI Gene ID:	3725
NCBI Accession:	P05412.2
UniProt Secondary Accession:	P05412,Q6FHM7, Q96G93,
UniProt Related Accession:	P05412
Molecular Weight:
NCBI Full Name:	Transcription factor AP-1
NCBI Synonym Full Names:	jun proto-oncogene
NCBI Official Symbol:	JUN
NCBI Official Synonym Symbols:	AP1; AP-1; c-Jun
NCBI Protein Information:	transcription factor AP-1
UniProt Protein Name:	Transcription factor AP-1
UniProt Synonym Protein Names:	Activator protein 1; AP1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog; p39
Protein Family:	C-Jun-amino-terminal kinase-interacting protein
UniProt Gene Name:	JUN
UniProt Entry Name:	JUN_HUMAN

Phospho-c-Jun (Ser73)In-Cell ELISA

The Phospho-c-Jun (Ser73) In Cell ELISA Kit is specifically designed for the precise measurement of phosphorylated c-Jun (Ser73) levels in cell lysates. This kit offers exceptional sensitivity and specificity, leading to consistent and accurate results, making it a valuable tool for various research applications.Phosphorylated c-Jun (Ser73) is a key transcription factor that regulates gene expression and plays a crucial role in cell proliferation, apoptosis, and differentiation. Understanding the activity and regulation of phosphorylated c-Jun can provide valuable insights into various cellular processes and diseases, such as cancer, inflammation, and neurodegenerative disorders.

With its high-performance capabilities, the Phospho-c-Jun (Ser73) In Cell ELISA Kit is an indispensable resource for researchers looking to study the intricate signaling pathways involving c-Jun and its phosphorylation status, ultimately advancing our understanding of complex cellular mechanisms.

Antibodies

Phospho-JUN/JUND (S73/100) Antibody (PACO06094)

JUN/JUND Antibody (PACO06253)