Description
Product Name: | Phospho-BRD4-T249 Polyclonal Antibody |
SKU: | CABP1515 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic phosphorylated peptide around T249 of human BRD4 (NP_490597.1). |
Tested Applications: | WB |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | CAP; MCAP; HUNK1; HUNKI; FSHRG4; Phospho-BRD4-T249 |
Positive Sample: | NIH/3T3+CA |
Conjugate: | Unconjugated |
Cellular Localization: | Chromosome, Nucleus. |
Calculated MW: | 152kDa |
Observed MW: | 200kDa |
The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described.
Purification Method: | Affinity purification |
Gene ID: | 23476 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thiomersal,50% glycerol,pH7.3. |