The Phospho-BRD4 (T204) Rabbit Polyclonal Antibody (CABP1124) is a vital tool for researchers studying the BRD4 protein and its phosphorylation at threonine 204. BRD4 is a key player in epigenetic regulation and gene expression, particularly in cancer cells where it plays a role in cell proliferation and survival.This antibody, raised in rabbits, specifically recognizes the phosphorylated form of BRD4 at threonine 204 in human samples, making it an ideal choice for Western blot applications. By targeting this specific phosphorylation site, researchers can gain insight into the role of BRD4 in cancer progression and potentially identify new therapeutic targets.
The Phospho-BRD4 (T204) Rabbit Polyclonal Antibody (CABP1124) is a valuable tool for researchers in the fields of cancer biology, epigenetics, and drug development. Its high reactivity and specificity make it an essential component in studies aimed at understanding the molecular mechanisms underlying cancer and identifying novel therapeutic strategies.
Antibody Name:
Anti-Phospho-BRD4-T204 Antibody
Antibody SKU:
CABP1124
Antibody Size:
20uL, 50uL, 100uL
Application:
WB
Reactivity:
Human, Mouse, Rat
Host Species:
Rabbit
Immunogen:
A phospho specific peptide corresponding to residues surrounding T204 of human BRD4.
Application:
WB
Recommended Dilution:
WB 1:500 - 1:2000
Reactivity:
Human, Mouse, Rat
Positive Samples:
NIH/3T3
Immunogen:
A phospho specific peptide corresponding to residues surrounding T204 of human BRD4.
Purification Method:
Affinity purification
Storage Buffer:
Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:
IgG
Sequence:
Email for sequence
Gene ID:
23476
Uniprot:
O60885
Cellular Location:
Chromosome, Nucleus
Calculated MW:
80kDa/88kDa/152kDa
Observed MW:
200KDa
Western blot - Phospho-BRD4-T204 Rabbit pAb (CABP1124)
The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]
