Phospho-Bcl-2-S70 Rabbit Polyclonal Antibody (CABP0575)
- SKU:
- CABP0575
- Product Type:
- Antibody
- Applications:
- WB
- IF
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | Phospho-Bcl-2-S70 Rabbit Polyclonal Antibody |
SKU: | CABP0575 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Rat |
Immunogen: | A synthetic phosphorylated peptide around S70 of human Bcl-2 (NP_000624.2). |
Sequence: | RTSP L |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | Bcl-2; PPP1R50; Phospho-Bcl-2-S70 |
Positive Sample: | Jurkat,293 |
Conjugate: | Unconjugated |
Cellular Localization: | Endoplasmic reticulum membrane, Mitochondrion outer membrane, Nucleus membrane, Single-pass membrane protein. |
Calculated MW: | 26kDa |
Observed MW: | 28kDa |
This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 596 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |