Phospho-Bcl-2-S87 Rabbit Polyclonal Antibody (CABP1071)
- SKU:
- CABP1071
- Product Type:
- Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
| Product Name: | Phospho-Bcl-2-S87 Rabbit Polyclonal Antibody |
| SKU: | CABP1071 |
| Size: | 20uL, 100uL |
| Isotype: | IgG |
| Host Species: | Rabbit |
| Reactivity: | Human,Rat |
| Immunogen: | A synthetic phosphorylated peptide around S87 of human Bcl-2 (NP_000624.2). |
| Sequence: | ALSP V |
| Tested Applications: | WB ELISA |
| Recommended Dilution: | WB,1:500 - 1:2000 |
| Synonyms: | Bcl-2; PPP1R50; Phospho-Bcl-2-S87 |
| Positive Sample: | C6 |
| Cellular Localization: | Endoplasmic reticulum membrane, Mitochondrion outer membrane, Nucleus membrane, Single-pass membrane protein. |
| Calculated MW: | 26kDa |
| Observed MW: | 28kDa |
This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.
| Purification Method: | Affinity purification |
| Gene ID: | 596 |
| Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |
 | Western blot analysis of lysates from C6 cells, using Phospho-Bcl-2-S87 Rabbit pAb (CABP1071) at 1:1000 dilution.C6 cells were treated by Paclitaxel (100 nM) at 37℃ for 20 hours.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% BSA.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s. |
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