Phospho-Axl-Y702 Polyclonal Antibody (CABP0848)
- SKU:
- CABP0848
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Developmental Biology
Frequently bought together:
Description
Product Name: | Phospho-Axl-Y702 Polyclonal Antibody |
SKU: | CABP0848 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic phosphorylated peptide around Y702 of human AXL (NP_068713.2). |
Sequence: | GDYY R |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:100 - 1:500 |
Synonyms: | ARK; UFO; JTK11; Tyro7; Phospho-Axl-Y702 |
Positive Sample: | A-549 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Single-pass type I membrane protein. |
Calculated MW: | 98kDa |
Observed MW: | 138kDa |
The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. The encoded protein acts as a host cell receptor for multiple viruses, including Marburg, Ebola and Lassa viruses and is a candidate receptor for the SARS-CoV2 virus.
Purification Method: | Affinity purification |
Gene ID: | 558 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |