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Phospho-AURKA-T288/AURKB-T232/AURKC-T198 Rabbit Polyclonal Antibody (CABP0948)

SKU:
CABP0948
Product Type:
Antibody
Reactivity:
Human
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
€419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Phospho-AURKA-T288/AURKB-T232/AURKC-T198 Rabbit Polyclonal Antibody
SKU:CABP0948
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Rat
Immunogen:A synthetic phosphorylated peptide around T288 of human AURKA/AURKB/AURKCAURKA (NP_003591.2).
Sequence:RTTL C
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:2000
Synonyms:AURKA/AURKB/AURKC; Phospho-AURKA-T288/AURKB-T232/AURKC-T198
Positive Sample:HeLa
Cellular Localization:basolateral plasma membrane, centriole, centrosome, ciliary basal body, cytosol, germinal vesicle, glutamatergic synapse, meiotic spindle, microtubule cytoskeleton, mitotic spindle, mitotic spindle pole, nucleoplasm, nucleus, perinuclear region of cytoplasm, pronucleus, spindle, spindle midzone, spindle pole centrosome
Observed MW:35KkDa/48kDa

The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Purification Method:Affinity purification
Gene ID:6790/9212/6795
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from HeLa cells, using Phospho-AURKA-T288/AURKB-T232/AURKC-T198 Rabbit pAb (CABP0948) at 1:1000 dilution.Hela cells were treated by ATP(5 mM) at 30℃ for 1 hour.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% BSA.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.

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