Phospho-ATF4-S245 Rabbit Polyclonal Antibody (CABP0309)
- SKU:
- CABP0309
- Product Type:
- Antibody
- Applications:
- WB
- IHC
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Product Name: | Phospho-ATF4-S245 Rabbit Polyclonal Antibody |
SKU: | CABP0309 |
Size: | 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A phospho specific peptide corresponding to residues surrounding S245 of human ATF4 |
Tested Applications: | WB |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | CREB2; TXREB; CREB-2; TAXREB67; Phospho-ATF4-S245 |
Positive Sample: | HeLa |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm, Nucleus, centrosome, cytoskeleton, microtubule organizing center. |
Calculated MW: | 39kDa |
Observed MW: | 45kDa |
This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication.
Purification Method: | Affinity purification |
Gene ID: | 468 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |